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Tannic acid may reduce footpad dermatitis in poultry

Dietary tannic acid supplementation 饲料级单宁酸may not affect the growth performance, intestinal viscosity, and litter quality. However, it may reduce the incidence and severity of FPD in broiler chickens. Feed supplemented with tannic acid饲料级单宁酸 may offer a foot health boost to poultry by reducing occurrence and severity of footpad dermatitis, say researchers.

缩合单宁在反刍动物生产中的作用:进展,局限性和未来方向

单宁酸(饲用单宁酸)是植物中最丰富的多酚类化合物之一。单宁酸(饲用单宁酸)在自然界中作为多种化学上独特的实体存在。最常见的单宁酸(饲用单宁酸)通常根据化学结构分为两大类:水解单宁(HT)或缩合单宁(CT)。水解性单宁酸(饲用单宁酸)是没食子酸或鞣花酸的酯类,与多元醇核(通常是葡萄糖)相连。缩合单宁酸(饲用单宁酸)或原花青素由黄烷-3-醇亚单位连接在一起形成低聚物和聚合物组成。HT和CT都被定义为收敛性的中高分子量的多酚类化合物,其特点是与可溶性蛋白质结合并沉淀。本文的目的是介绍CT与反刍动物相互作用的最新进展、理解和使用CT在反刍动物生产中的局限性,以及未来研究的需求,以进一步提高我们对CT在优化反刍动物生产中的作用的认识。凝聚态单宁酸(饲用单宁酸)对反刍动物造成了一定的抗营养问题,因为它的收敛性降低了饲料的采食量,从而降低了动物的性能。然而,反刍动物可以通过瘤胃微生物慢慢适应CT的毒性作用,并释放出与CT结合的唾液蛋白,从而耐受CT。CT的蛋白质结合能力对反刍动物有一定的好处,因为CT与必需氨基酸形成复合物,防止其在瘤胃中降解,但在下层肠道中释放出来供动物吸收。最近的数据表明,给生长中的动物使用CT时,N的保留量会增加。由于CT和HT具有抑制胃肠道线虫寄生虫的卵孵化和幼虫运动的能力,特别是在小型反刍动物中,使用CT和HT具有潜在的抗病毒作用。

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The role of condensed tannins in ruminant animal production: advances, limitations and future directions

Tannins (饲用单宁酸) represent one of the most abundant polyphenolic compounds in plants. Tannins (饲用单宁酸) exist as a multitude of chemically unique entities in nature. The most commonly occurring tannins (饲用单宁酸) are typically divided into two major classes based on chemical structure: hydrolysable (HT) or condensed tannins (饲用单宁酸) (CT). Hydrolysable tannins (饲用单宁酸) are esters of gallic or ellagic acid linked to a polyol core, typically glucose. Condensed tannins (饲用单宁酸) or proanthocyanidins consist of flavan-3-ol subunits linked together to form oligomers and polymers. Both HT and CT are defined as astringent, medium-to-high-molecular weight polyphenolic compounds that characteristically bind and precipitate soluble proteins. The objective of this paper was to present recent advances in CT-ruminant interactions, the limitations associated with understanding and using CT in ruminant animal production, and future needs for research to further advance our knowledge of the role of CT in optimization of ruminant animal production. Condensed tannins (饲用单宁酸) pose some anti-nutritional problems to ruminants due to their astringent property that reduces feed intake and, consequently, animal performance. Ruminants can, however, tolerate CT by slowly adapting the ruminal microbes to the toxic effects of CT and by releasing CT-binding salivary proteins. The protein-binding ability of CT has some benefits to the ruminant due to complexes formed with essential amino acids, preventing their degradation in the rumen, but releasing them in the lower gut for absorption by the animal. Recent data have suggested increased N retention when CT is given to growing animals. There are potential benefits of using CT and HT for anthelmintic purposes due to their ability to inhibit egg hatching and larval motility of gastrointestinal nematode parasites, especially in small ruminants.

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植物化学物质饲料级单宁酸作为抗生素替代品,可促进生长并增强宿主健康

全球范围内对新出现的耐药性超级细菌以及缺乏治疗人类和动物疾病的新抗生素的担忧日益增加。对于农业产业而言,迫切需要制定饲料级单宁酸战略,以替代抗生素治疗粮食生产动物,特别是家禽和牲畜。在动物健康和生产中使用抗生素的替代品;评估与其商业化相关的挑战;制定可操作的战略,以促进开发抗生素生长促进剂(AGPs)的替代品饲用单宁酸,同时不妨碍动物生产。科学会议,包括疫苗、微生物产品、植物化学物质、免疫相关产品以及创新药物、化学品和酶等。

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Phytochemicals 饲料级单宁酸as antibiotic alternatives to promote growth and enhance host health

There are heightened concerns globally on emerging drug-resistant superbugs and the lack of new antibiotics for treating human and animal diseases. For the agricultural industry, there is an urgent need to develop strategies 饲料级单宁酸 to replace antibiotics for food-producing animals, especially poultry and livestock. Alternatives to antibiotics for use in animal health and production; assess challenges associated with their commercialization; and devise actionable strategies to facilitate the development of alternatives 饲用单宁酸 to antibiotic growth promoters (AGPs) without hampering animal production. The 3-day meeting consisted of four scientific sessions including vaccines, microbial products, phytochemicals, immune-related products, and innovative drugs, chemicals and enzymes.

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饲用单宁酸作为家禽中抗菌生长促进因子的替代品

抗生素类化合物最初是以治疗性剂量添加到饲料中,用于治疗和预防传染病,但很快就发现了抗生素的促进生长作用。因此,从20世纪50年代初开始,在饲料中添加抗生素,以提高饲料利用率和养殖动物的生长,降低生产成本。饲料单宁酸作为促进生长因子(AGP)的抗生素的使用应与治疗性和预防性使用的抗生素区别开来,因为抗生素的使用剂量大、时间短,所以在饲料中使用抗生素的剂量和时间较长。

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Tannins as an alternative to antimicrobial growth promoter factors in poultry

Antimicrobial compounds were initially added to feed at therapeutic doses for treatment and prevention of infectious diseases but soon the growth promoting effect of antibiotics was observed. Therefore, since the beginning of the 1950s antibiotics have been added to feeds to improve feed utilization and growth of farm animals, reducing the cost of production. 饲料单宁酸The use of antimicrobials as growth-promoting factors (AGP) should be distinguished from therapeutic and prophylactic use of antibiotics that are administrated at higher doses and for short periods of time.

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饲用单宁酸作为饲料中抗生素的替代品在养殖业生产中的潜力和挑战

单宁酸饲用单宁酸传统上被认为是单胃动物和家禽的 “抗营养因子”,但最近的研究发现,当以适当的方式应用其中的一些单宁酸时,可以改善肠道微生物生态系统,增强肠道健康,从而提高生产性能。植物单宁酸饲料单宁酸作为饲料中抗生素的替代物的适用性取决于许多因素,这些因素导致其观察到的药效存在很大的差异性。

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Potential and challenges of tannins as an alternative to in-feed antibiotics for farm animal production

Tannins饲用单宁酸 have traditionally been regarded as “anti-nutritional factor” for monogastric animals and poultry, but recent researches have revealed some of them, when applied in appropriate manner, improved intestinal microbial ecosystem, enhanced gut health and hence increased productive performance. The applicability of plant tannins 饲料单宁酸 as an alternative to in-feed antibiotics depends on many factors that contribute to the great variability in their observed efficacies.

关于饲用单宁酸的安全性和有效性的科学意见书

饲用单宁酸在自然界中广泛分布。使用单宁酸作为饲料添加剂,高达15毫克/千克饲料是所有动物物种是安全的。在建议的使用条件下,使用单宁酸作为饲料添加剂对消费者没有安全风险。在没有数据的情况下,谨慎的做法是将添加剂视为对工人具有潜在危险,接触皮肤、眼睛和粘膜或吸入接触。单宁酸天然存在于许多植物物种中。使用单宁酸作为饲料添加剂被认为是对环境安全的。单宁酸被公认为食品调味剂,并被列入欧盟食品调味剂清单。由于它在饲料中的功能与食物的功能基本相同,因此无需进一步证明疗效。